COLON SPECIFIC DRUG DELIVERY SYSTEMS: A REVIEW ON PHARMACEUTICAL APPROACHES WITH CURRENT TRENDS

In recent years colon specific drug delivery has gained importance not just for the delivery of drugs for the treatment of local diseases associated with the colon but also as potential site for the systemic delivery of drugs like therapeutic proteins and peptides. This article reviews a detailed study about diseases of colon, diagnosis of diseases of colon, limitations and challenges, applications, anatomy of colon, factors affecting colon and different approaches of colon which include some current new approaches such as Pulsinicap system, Port system, Probiotic approach, Chronotropic system, Colal-pred system, Multiparticulate system, Enterion capsule technology and some past studies of colon drug delivery and also a study on evaluation for site specific drug delivery to colon.