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Binding Agents from Cassia Species

Keywords: Pharmaceutical excipients , Hydrodrophilic material , Xanthan gum , Cassia grandis , Cassia angustifolia , Guar , Cassia tora , Xanthan , Carboxymethyl gum.

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Abstract:

The present paper describes novel excipients from Cassia species for their use as binding agents in pharmaceutical formulations. Experiment revealed it to be a slow release pharmaceutical excipient of an inert diluent and a hydrodrophilic material including xanthan gum and galactomannan gums capable of cross-linking the xanthan gum in the presence of aqueous solutions that are parallely utilized for quick release tablet formulation. This paper waves off the difficulty of pharmacist who earlier used to face unacceptable flow characteristics and compressibility factors of the crystalline or powdered medicament. It possess flow ability, sufficient particle size distribution, binding ability, acceptable bulk and tap densities, and acceptable dissolution and disintegration properties in order to release the medicament upon oral administration.

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