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Sensors 2013

Piper nigrum, Piper betle and Gnetum gnemon- Natural Food Sourcewith Anti-Quorum Sensing Properties

DOI: 10.3390/s130303975

Li Ying Tan,Wai-Fong Yin,Kok-Gan Chan

Keywords: natural products, Pseudomonas aeruginosa, pathogenicity, pyocyanin, quorum sensing, quorum quenching, swarming, violacein, virulence

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Abstract:

Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [pSB1075] and Chromobacterium violaceum CV026. It was found that the extracts of these three plants have anti-QS ability. Interestingly, the hexane, chloroform and methanol extracts from P. betle showed the most potent anti-QS activity as judged by the bioassays. Since there is a variety of plants that serve as food sources in Malaysia that have yet to be tested for anti-QS activity, future work should focus on identification of these plants and isolation of the anti-QS compounds.

References

[1]	Waters, C.M.; Bassler, B.L. Quorum sensing: Cell-to-cell communication in bacteria. Annu. Rev. Cell Dev. Biol. 2005, 21, 319–346.
[2]	Reading, N.C.; Sperandio, V. Quorum sensing: The many languages of bacteria. FEMS Microbiol. Lett. 2006, 254, 1–11.
[3]	Taga, M.E. Bacterial signal destruction. ACS Chem. Biol. 2007, 2, 89–92.
[4]	Bassler, B.L. How bacteria talk to each other: Regulation of gene expression by quorum sensing. Curr. Opin. Microbiol. 1999, 2, 582–587.
[5]	Duran, N.; Menck, C.F.M. Chromobacterium violaceum: A review of pharmacological and industrial perspectives. Crit. Rev. Microbiol. 2001, 27, 201–222.
[6]	Teoh, A.Y.B.; Hui, M.; Ngo, K.Y.; Wong, J.; Lee, K.F.; Lai, P.B.S. Fatal septicaemia from Chromobacterium violaceum: Case reports and review of the literature. Hong Kong Med. J. 2006, 12, 228–231.
[7]	Blosser, R.S.; Gray, K.M. Extraction of violacein from Chromobacterium violaceum provides a new quantitative bioassay for N-acyl homoserine lactone autoinducers. J. Microbiol. Methods. 2000, 40, 47–55.
[8]	McClean, K.H.; Winson, M.K.; Fish, L.; Taylor, A.; Chhabra, S.R.; Camara, M.; Daykin, M.; Lamb, J.H.; Swift, S.; Bycroft, B.W.; et al. Quorum sensing and Chromobacterium violaceum: Exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology 1997, 143, 3703–3711.
[9]	Eberl, L.; Tummler, B. Pseudomonas aeruginosa and Burkholderia cepacia in cystic fibrosis: Genome evolution, interactions and adaptation. Int. J. Med. Microbiol. 2004, 294, 123–131.
[10]	Smith, R.S.; Iglewski, B.H.P. aeruginosa quorum-sensing systems and virulence. Curr. Opin. Microbiol. 2003, 6, 56–60.
[11]	Whitehead, N.A.; Barnard, A.M.L.; Slater, H.; Simpson, N.J.L.; Salmond, G.P.C. Quorum-sensing in gram-negative bacteria. FEMS Microbiol. Rev. 2001, 25, 365–404.
[12]	Storey, D.G.; Ujack, E.E.; Rabin, H.R.; Mitchell, I. Pseudomonas aeruginosa lasR transcription correlates with the transcription of lasA, lasB, and toxA in chronic lung infections associated with cystic fibrosis. Infect. Immun. 1998, 66, 2521–2528.
[13]	Hong, K.W.; Koh, C.L.; Sam, C.K.; Yin, W.F.; Chan, K.G. Quorum quenching revisited- from signal decays to signaling confusion sensors. Sensors 2012, 12, 4661–4696.
[14]	Wong, C.S.; Yin, W.F.; Sam, C.K.; Koh, C.L.; Chan, K.G. Characterisation of wetland quorum quenching Pseudomonas aeruginosa strain 2SW8 and its 2-heptyl-3-hydroxy-4-quinolone production. New Microbiol. 2012, 35, 43–51.
[15]	Chong, T.M.; Koh, C.L.; Sam, C.K.; Choo, Y.M.; Yin, W.F.; Chan, K.G. Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest. Sensors 2012, 12, 4846–4859.
[16]	Wong, C.S.; Yin, W.F.; Choo, Y.M.; Sam, C.K.; Koh, C.L.; Chan, K.G. Coexistence of quorum-quenching and quorum-sensing in tropical marine Pseudomonas aeruginosa strain MW3A. World J. Microbiol. Biotechnol. 2012, 28, 453–461.
[17]	Yin, W.F.; Tung, H.J.; Sam, C.K.; Koh, C.L.; Chan, K.G. Quorum quenching Bacillus sonorensis isolated from soya sauce fermentation brine. Sensors 2012, 12, 4065–4073.
[18]	Choo, J.H.; Rukayadi, Y.; Hwang, J.-K. Inhibition of bacterial quorum sensing by vanilla extract. Lett. Appl. Microbiol. 2006, 42, 637–641.
[19]	Vatte, D.A.; Mihalik, K.; Crixell, S.H.; McLean, R.J.C. Dietary phytochemicals as quorum sensing inhibitors. Fitoterapia 2007, 78, 302–310.
[20]	Bauer, W.D.; Teplitski, M. Can plants manipulate bacterial quorum sensing? Aust. J. Plant Physiol. 2001, 28, 913–921.
[21]	Tan, L.Y.; Yin, W.F.; Chan, K.G. Silencing quorum sensing through extracts of Melicope lunu-ankenda. Sensors 2012, 12, 4339–4351.
[22]	Krishnan, T.; Yin, W.F.; Chan, K.G. Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa PA01 by Ayurveda spice clove (Syzgium aromaticum) bud extract. Sensors 2012, 12, 4016–4030.
[23]	Chong, Y.M.; Yin, W.F.; Ho, C.Y.; Mustafa, M.R.; Hadi, A.H.A.; Awang, K.; Narrima, P.; Koh, C.L.; Appleton, D.R.; Chan, K.G. Malabaricone C from Myristica cinnamomea exhibits anti quorum sensing activity. J. Nat. Prod. 2011, 74, 2261–2261.
[24]	Rao, M.R.; Rajeswara Rao, B.R. Medicinal Plants in Tropical Homegardens. In Tropical Homegardens, 1st ed.; Kumar, B.M., Nair, P.K.R., Eds.; Springer Netherlands: Dordrecht, The Netherlands, 2006; Volume 3, pp. 205–232.
[25]	Arambewela, L.S.R.; Arawwawala, L.D.A.M.; Ratnasooriya, W.D. Antidiabetic activities of aqueous and ethanolic extracts of Piper betle leaves in rats. J. Ethnopharmocol. 2005, 102, 239–245.
[26]	Mali, W.; Naoki, I.; Hiroyuki, T.; Witchuda, T.; Hirochi, N. Inhibitory effects of Piper betle on production of allergic mediators by bone marrow-derived mast cells and lung epithelial cells. Int. Immunopharmacol. 2008, 8, 453–457.
[27]	Eishin, K.; Yuji, T.; Fujio, S. Stilbenoids isolated from the seeds of Melinjo (Gnetum gnemon L.) and their biological activity. J. Agric. Food Chem. 2009, 57, 2544–2549.
[28]	Winson, M.K.; Swift, S.; Fish, L.; Throup, J.P.; Jorgensen, F.; Chhabra, S.R.; Bycroft, B.W.; Williams, P.; Stewart, G.S. Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing. FEMS Microbiol. Lett. 1998, 163, 185–192.
[29]	Martinelli, D.; Grossmann, G.; Sequin, U.; Brandl, H.; Bachofen, R. Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum. BMC Microbiol. 2004, 4, 25.
[30]	Winzer, K.; Falconer, C.; Garber, N.C.; Diggle, S.P.; Camara, M.; Williams, P. The Pseudomonas aeruginosa lectins PA-IL and PA-IIL are controlled by quorum sensing and by RpoS. J. Bacteriol. 2000, 182, 6401–6411.
[31]	Essar, D.W.; Eberly, L.; Hadero, A.; Crawford, I. Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: Interchangeability of the two anthranilate synthases and evolutionary implications. J. Bacteriol. 1990, 172, 884–900.
[32]	Hayouni, E.A.; Bouix, M.; Abedrabba, M.; Leveau, J.-Y.; Hamdi, M. Mechanism of action of Melalueca armillaris (sol. ex gaertu) sm. essential oil on six lab strains as assessed by multiparametric flow cytometry and automated microtiter-based assay. Food Chem. 2008, 111, 707–718.
[33]	Konzen, M.; Marco, D.D.; Cordova, C.A.S.; Vieira, T.O.; Antonio, R.G.; Creczynski-Pasa, T.B. Antioxidant properties of violacein: Possible relation on its biological function. Bioorg. Med. Chem. 2006, 14, 8307–8313.
[34]	Teplitski, M.; Robinson, J.B.; Bauer, W.D. Plants secrete substances that mimic bacterial N-acyl homoserine lactone signal activities and affect population density-dependent behaviors in associated bacteria. Mol. Plant Microbe Interact. 2000, 13, 637–648.
[35]	Zhu, H.; Sun, S.J. Inhibition of bacterial quorum sensing-regulated behaviors by Tremella fuciformis extract. Curr. Microbiol. 2008, 57, 418–422.
[36]	Adonizio, A.L.; Downum, K.; Bennett, B.C.; Mathee, K. Anti-quorum sensing activity of medicinal plants in southern Florida. J. Ethnopharmacol. 2006, 105, 427–435.
[37]	Gerene, M.D.; Michelle, A.R.; George, T.R.; Charles, D.C.; Bradley, E.B. Psedomonas pyocyanin alters calcium signaling in human airway epithelial cells. AJP Lung Physiol. 1998, 274, 893–900.
[38]	Rasmussen, T.B.; Manefield, M.; Andersen, J.B.; Eberl, L.; Uffe, A.; Carsten, C.; Peter, S.; Staffan, K.; Michael, G. How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1. Microbiology 2000, 146, 3237–3244.
[39]	Pilar, T.; Angel, G.-I.; Francisco, T.-B.; Ana, A. Inhibition by chestnut honey of N-acyl-L-homoserine lactones and biofilm formation in Erwinia carotovora, Yersinia enterocolitica, and Aeromonas hydrophila. J. Agric. Food Chem. 2009, 57, 11186–11193.
[40]	Joemar, C.T.; Jusal, P.Q.; Rose, M.G.P.; Evangline, C.A.; Windell, L.R. Tannin-rich fraction from Terminalia catappa inhibits quorum sensing (QS) in Chromobacterium violaceum and the QS-controlled biofilm maturation and LasA staphylolytic activity in Pseudomonas aeruginosa. J. Ethnopharmacol. 2011, 134, 865–871.
[41]	Khee, H.K.; Foong-Yee, T. Screening of traditional chinese medicinal plants for quorum-sensing inhibitors activity. J. Microbiol. Immunol. Infect. 2011, 44, 144–148.
[42]	Gulgun, B.-T.; Seyhan, U.; Aysel, U.; Ozgur, C. Inhibition of quorum sensing-regulated behaviors by Scorzonera sandrasica. Curr. Microbiol. 2007, 55, 114–118.
[43]	Quave, C.I.; Plano, L.R.W.; Pantuso, T.; Bennett, B.C. Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus. J. Ethnopharmacol. 2008, 118, 418–428.

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