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Audiology  2012 

Effect of Prophylactic Drugs on Vestibular Evoked Myogenic Potential in Migraine Patients

Keywords: Vestibular Evoked Myogenic Potential , Prophylactic Drugs , Vestibular System , Migraine

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Abstract:

Background and Aim: In many migraine patients prophylactic drugs are effective in reducing attacks and symptoms such as vestibular complaints. Therefore, related neural pathways are probably alsoaffected. This study aimed to compare vestibular evoked myogenic potential in migraine patients under treatment with prophylactic drugs and those without any treatment.Methods: Subjects included 46 patients with migraine. They were evaluated in two groups; those under treatment with prophylactic drugs (21 subjects) and those without treatment (25 subjects). Theage range of patients was 20-60 years. The vestibular evoked myogenic potential were recorded with 500 Hz tone bursts at 95 dB nHL.Results: Mean of amplitude ratio (p=0.02), and interpeak latency values in the right ear (p=0.03) and left ear (p=0.001) were higher in patients with prophylactic therapy than the group without therapy;this difference was statistically significant. There was no statistical difference between the two groups in terms of mean of latency of p13 and n23 peaks, and absolute amplitude (p>0.05).Conclusion: Prophylactic drugs probably improve mean of main response parameters of vestibular evoked myogenic potential in migraine patients with prophylactic therapy.

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