The effect of different laterals and emitters frequency on growth, leaf content of N, P, K, Mg, S, Zn, Fe and Mn, berry setting, yield as well as physical and chemical characteristics of superior grapes were investigated during 2009 and 2010 seasons. Eight years old superior grape vines grown at 1.75x2.75 m apart in sandy loam soil in Qena Governorate under drip irrigation system with 4 L h-1 emitters were used in this study. One or two laterals and two to six emitters per vine were used. Results revealed that leaf area, main shoot length, leaf content of N, P, K, Mn, S, Zn, Fe and Mn, berry setting, yield, cluster weight as well as physical and chemical characteristics of the grapes markedly improved with increasing number of laterals from one to two and number of emitters from two to six. Increasing emitters' frequency from four to six on double laterals gave significant effect on the above mentioned characters. The best recommended treatment for increasing irrigation water utilization efficiency in Superior vineyards as well as improving yield quantitatively and qualitatively is double laterals and six emitters/ vine.