The objective of the present study was to verify the effects of two frequencies (100 and 33%) of knowledge of results (KR) on the learning of a motor skill, in individuals with Down syndrome (DS). Twenty participants with DS were randomly assigned into two groups. While the 100% group received KR after each trials, the 33% group received KR in a third of the trials. The task consisted of throwing an implement on a target, with the dominant hand, while blindfolded. The acquisition phase consisted of 30 practice trials, while the retention phase, performed after 48 hours later, consisted of 10 trials without KR. The results showed no differences between the groups. We concluded that reduced relative frequencies of KR are as effective as high frequencies on the learning of simple motor tasks in adults with DS.