The aim of this study was to investigate the prevalence of trypanosomosis in white Fulani cattle in Ladduga District, Kachia LGA of Kaduna State and further highlight the importance of human behavior, belief, attitude and activity in the epidemiology and control of African trypanosomosis. A total of 65 animals were sampled randomly. Blood collected from the jugular vein was stored in heparinized blood containers. The standard trypanosomosis diagnostic method was employed. An overall infection rate of 29.2% was recorded in the herd with bulls accounting for 20.0% and cows 32.0%. The average Packed Cell Volume (PCV) of infected animals (23.6±0.4%) was lower than non-infected (36.4±0.7%). These values were statistically significant (p<0.05). Clinical signs observed were lacrimation, pale mucus membrane, rough hair coat and presence of ticks. However, despite good appetite and availability of forage, emaciation was observed in 29 animals (45.0%). The trypanosomes encountered were T. vivax (42.0%), T. congolense (15.7%), T. brucei (21.0%) and mixed infection (21.0%). Traps caught only biting flies; Tabanus and Stomoxy species.