The study was undertaken to examine the state of quality assurance mechanisms in Nigerian universities with a view to proffering measures that would enhance the quality of education obtained in the institutions. The population consisted of professors from federal universities in the south-south region of Nigeria, numbering 624. The stratified sampling technique was used in selecting a sample of 225 professors from the universities for the study. Two null hypotheses were formulated based on the variables of the study. These were tested at 0.05 alpha level, using t-test analysis. Data collection was done with the use of a structured questionnaire tagged “Quality Assurance in Nigerian University Education” (QANUE). The calculated t-values were less than the criticalt, leading to the retention of the two null hypotheses. It was therefore concluded that the quality of Nigerian University Education is low and cannot measure up globally due to the poor state of quality assurance mechanisms in the universities. Based on this, measures for improving the quality of Nigerian university education were recommended to include adequate funding, updated libraries, well equipped laboratories and workshops, provision of instructional materials and school infrastructure, lecturer motivation and proper supervision.