One hundred sixty two patients of osteoarthritis (OA)knee were studied to describe their clinical profile. Thepatients were included according to the criteria developedby the American College of Rheumatology. Detailedhistory, clinical examination and X-rays were carried out.The data were analysed statistically and the results wereexpressed in percentage and frequency. In this study, 96(59.3%) were male and 66 (40.7%) were female. Themean age of the subject was 53.73 ± 11.35 years. Mostof the patients of were in the age group of 50 to 59 years.Maximum number of females in the age group of 35 to45 years was affected. Most of the males were affectedin the later ages, between 55 to 65 years. Most of thepatients were middle class (68.5%) and housewives(35.8%). Mean height was 159.99 ± 8.12 cm and meanweight was 63.34 ± 11.60 kg. Mean duration of symptomswas 25.25 ± 38.85 months. Most patients gave the historyof gradual onset of the pain (87.7%). Most of the patientshad no morning stiffness in the knee (90.1%). Morningstiffness was present in 9.3% but it was for less than onehour. Maximum patients had intermittent pain (53.7%)but 46.3% patients had constant pain. By this study, itcan be concluded that OA knee is commoner in malesbut females develop it earlier in the life than the males.