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Short Term Rehabilitative Outcome and its Predictors in Guillain Barré Syndrome

Keywords: Guillain Barré Syndrome , rehabilitation , outcome predictors

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Abstract:

Clinical and electrophysiological data of 34 patientssuffering from Guillain Barré Syndrome (GBS) wereanalyzed. Functional disability and predictors of outcomewas determined using Hugh’s scale and MedicalResearch Council (MRC) scale at 0, 2 and at 4 weeks.Good outcome was defined as the ability to ambulatewithout assistance. 56% patients were males with meanage of 18.41 years (SD ±13.88). Preceding illness wasseen in 76.5%. Mean days to disease nadir was 4.6 days.Weakness (50%) was the predominant chief complaint.Mechanical ventilation was required in 41.2 % patientswith a mortality of 7.1%. Independent ambulation wasachieved by 61.8% and 17.6% with support at the end ofstudy period. Increasing age (p<0.01), days to nadir(p=0.00), duration of ventilation (p<0.001), severity ofmotor deficit at disease nadir (p<0.001) and high Hugh’sscore (p=0.00) affected outcome. Mechanicallyventilated patients had poorer outcome. Although therecovery from severe GBS was prolonged, most survivorsregained independent ambulation.

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