Common indications of sedation in the PICU (Pediatric intensive care unit) include mechanical Ventilation and various procedures performed in the PICU and in radiology or endoscopy suites. Sedation potentiates the effect of narcotics, thereby ensuring better comfort and analgesia. Sedation is a mandatory prerequisite prior to and during administration of neuromuscular blockers. This review includes practical pharmacology and uses of commonly used agents in the PICU.
