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Phytochemical studies and pharmacological screening of Sida rhombifolia Linn.

Keywords: Sida rhombifolia Linn. , Anti-anxietyactivity

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Abstract:

Plan: Anti-anxiety activity of Sida rhombifolia Linn.Prologue: Sida rhombifolia commonly called Bala or Atibala is claimed by folklorefor various ailments like rheumatism, seminal weakness, and diarrhea. Earlier studies on the ethanolic extract of theroots (SRE) revealed a significant, antioxidant, antimicrobial,anti-inflammatory, hepatoprotective and antibacterial activity. The presentstudy was designed to evaluate anti-anxiety activity of powdered whole plantextracts of Sida rhombifolia Linn. viz petroleum ether and ethanol.Methodology: Anti-anxiety activity of Sida rhombifolia Linn. were studied byusing Elevated Plus Maze (EPM) model in albino mice.Outcome: Albino mice were treated orally with dose 300 mg/kg of the extract andbehavior was observed on the EPM. Diazepam (2mg/kg, P.O) was used as a positivecontrol. Result showed that alcoholic extract was found to produce verysignificant result. Hence, this plant may be developed as a potentially usefulanti anxiety agent

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