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Anti-anxiety activity of Gloriosa superba Linn.

Keywords: Gloriosa supberba Linn. , Elevated plus Maze , anti-anxiety activity

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Abstract:

Plan: Anti-anxietyactivity of Gloriosa superba Linn. Prologue: Gloriosa supberbaLinn. (Family: Liliaceae) is widely used as a medicinal plant. Gloriosasuperba Linn. has several therapeutic applications including antinflammatory, anthelmintic,abotifacient, oxytocic, analgesic antimicrobial and mutagenic activities1-3. The petroleum ether and ethanol extracts of powdered aerial part ofGloriosa superb Linn. were studied foranti-anxiety activity.Methodology: Anti-anxiety activity of G. supberbaLinn were studied by using Elevated PlusMaze (EPM) model in albino mice.Outcome: Albino mice weretreated orally with dose 300 mg/kg of the extracts and behavior was observed onthe EPM. Diazepam (2mg/kg, P.O) was used as a positive control. The resultsindicated that alcoholic extract exhibited significant result as compared tothe standard drug.Keywords: Gloriosa supberba Linn., Elevated plus Maze, anti-anxiety activity

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