This paper investigates any difference in employing Reading strategies, relates them to various item types of reading comprehension in TOEFL iBT (copyrighted by ETS, 2005). Sixty-six respondents (26 males and 40 females) participated in the present study. A list of reading strategies (adopted from Cohen & Upton, 2006), followed by a test of reading comprehension that took forty-five minutes to complete were used. Before the test begun, the participants were instructed how to specify the strategies that they employed during taking the test. To address the research question, the analyses of the results revealed that the difference is significant in the use of Reading strategies for various item types. On the basis of the findings language teachers are recommended to teach different Reading strategies in order to help TOEFL applicants to use them related to different item types more efficiently and effectively.