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Cytologic smear study in patients with and without monopause

Keywords: Menopause , Cervical and vaginal infection , Bacterial vaginosis , Pap T , Vaginalis. G , vaginalis , Cocci , Lactobacilli.

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Introduction: The onset of menopause is given by the gradual decrease of estrogenlevels, eventually leading to the absence of menstruation, causing a major change inthe conditions governing the cervicovaginal environment. Some studies have reporteda high frequency of cervicovaginal infections in menopausal women.Objective: To identify cervical vaginal infectious diseases that occur in patients whohave gone through menopause and those who have not.Material and Methods: We analyzed the results of the interrogation and the cellularfootage from the cervical-vaginal canal of all patients attending the Laboratorio deBiología Celular de la Facultad de Medicina de la Benemérita Universidad Autónoma dePuebla, México (BUAP) the program on Early Detection of Cancer (DOC) or Pap smearsfrom 2001 to 2008. We analyzed the results of 196 postmenopausal women (group M)and 836 menopausal patients (group NM).Results: Based on the classification of Bethesda 2001, the M group, 29 cases (14.8%)were negative for malignancy, 167 cases (85.2%) reactive changes, there were no casesof Atypical Squamous Cells of Undetermined Significance ASCUS (for short English),squamous intraepithelial lesion of low grade (LSIL) squamous intraepithelial (HSIL),squamous cell carcinoma. NM group, 112 cases (13.4%) were negative for malignancy,704 cases (84.2%) with reactive changes, 0 cases (0.0%) ASCUS, 18 cases (2.2%)with LSIL, 2 cases (0.2%) with HSIL not found patients with squamous cell carcinoma(Figure 1). As cells aggregate, Leukocyte: group M. 153 cases (78.06%), NM group.730 cases (87.32%); Erythrocytes: M group 69 cases (35.2%), NM group 306 cases(36.60%). Mixed flora, viral Reaction: 0 (0%) M, 2 (0.24%) NM; T. vaginalis 13 (6.63%9 M, 52 (6.22%) NM, bacterial vaginosis: 109 (55.61%) M, 540 (64.59%) NM, Fungi:72 (36.73%) M, 232 (27.75%) NM; Parasites : 0 (0.00%) M, 0 (0.00%) NM; Cytolysis:13 (6.63%) M, 63 (7.54%) NM; Lactobacillus: 25 (12.76%) M, 205 (24.52%) NM.Conclusions: A high percentage of postmenopausal women and postmenopausalwomen not occur with cervicovaginal inflammation, the presence of lactobacilli is lowerin postmenopausal patients, encouraging fungal infections, an important frequency inmenopausal women with bacterial vaginosis, the menopause is not a factor risk forthe prevalence of infections with T. vaginalis viruses.RESUMEN:Introducción: la aparición de la menopausia está dada por la disminución paulatinade los niveles de estrógeno que llevan finalmente a la ausencia de la menstruación,generando un gran cambio en las condiciones que rigen el entorno cervicovaginal.Alguno


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