A ten-year-old neutered male dog was examined for tetraparesis, vestibular dysfunction, ataxia,and vertebral column hyperesthesia of 10 days duration. On magnetic resonance imaging (MRI),there were multifocal, punctate, T2-hyperintense lesions in the brain and cervical spinal cord andintracranial leptomeningeal contrast enhancement. Cerebrospinal fluid (CSF) analysis revealed apredominantly mononuclear pleocytosis and mildly elevated protein. Ehrlichia canis wasdiagnosed by serum immunofluorescent antibody (IFA) testing. The dog improved withadministration of doxycycline. This report describes MRI central nervous system findings in a dogwith ehrlichiosis.