Research results presented in this paper refer to changes in the structure of the agricultural population of the P inja District in the period from 1971 to 2002. They point to markedly decrease in the agricultural population, the share of agricultural population in total population, the share of rural population in total population, as well as the share of active agricultural population in total active population. The process of deagrarianization in this area is a constraining factor for the development of agriculture and causes spontaneous abandonment by working-age population who is employing in other sectors. Transfer of agricultural population in non-agricultural activities takes place either by moving into the city centre or by remaining in agricultural households and employing in non-agricultural activities (which causes daily rural-urban migration). The process of depopulation and deruralization caused ageing population to be involved in agriculture in many rural settlements so that the effects of agricultural production have become significantly decreasing. To eliminate the negative effects of the regional development of the P inja District, it is necessary to establish and implement a functional demographic policy and concept of the revitalization of rural area.