As one of the signs of demographic change, population aging influences various spatial categories: economic activities, social features, land-use, perspectives for future development and more. Even though the process is indicative on a national level, there are significant differences among geographically and functionally distinctive regions. Based on considerable regional differences in the development of Serbia, this paper analyses the key problems of rural areas related to the interdependences of population aging and agricultural activities. Research on aging processes, changes in agricultural activities and their features is based here on the examples of two case studies. The In ija and Knja evac Municipalities have been chosen to represent geographically different regions - lowland and mountainous. This study uses both quantitative and qualitative approaches in order to achieve a better understanding of the situation. Statistical data were used to illustrate processes of aging and agriculture where data from two census years indicate a trend of changes. Interviews conducted with representatives of local government, entrepreneurs and local citizens from the villages are the source of information for quantitative analysis. Population aging and agriculture are examined separately, followed by an illustration of their interdependences.