Introduction: Quality circle are considered an important approach to improving behavior, increasing motivation, and reducing stress. The aim of this study was to determining the effect of training and applying quality control circles on the nurses’ level of occupation satisfaction.Material and Methods: This research is a two-group quasi-experimental study that after selection of two EMS stations, by simple randomization method 25 nurses worked in central station of Hamden emergency medical service were chosen as the quality circle group and 16 nurses of central station of Malayer emergency medical service formed the control group. The tools was used in this research was the occupation satisfaction questionnaire that was made on Herzburg Two factor theory. After training and performing of quality circle in trial group the occupation satisfaction test was carried out on both groups to get the change taken place in their level of job satisfactions. Then statistical analysis was performed using SPSS.Results: The analysis of data showed that before and after intervention there was significant differences in scores of health (P<0.001) and motivation factors (P<0.001) and also in global scores of occupation satisfaction in quality circle group (P<0.001), but there was no significant differences before and after intervention in scores of health (P=0.069) and motivation factors (P=0.094) and also in global scores of occupation satisfaction in control group (P=0.495). After intervention, the analysis of data showed significant differences in scores motivation factors (P=0.001) and global scores of occupation satisfaction (P=0.003) whereas there was no significant differences in scores of health factors between two groups (P=0.089).Conclusion: This study confirmed the effectiveness of training and applying quality circle in improving EMS nurses job satisfaction and offered as management method for use by EMS managers.