Hydatidosis is one of the major zoonotic diseases that cause considerable economic losses and public health problems worldwide. The present study was conducted to determine the prevalence of E. granulosus in domestic and wild carnivores and the infection rate of hydatid cyst in slaughtered animals and people in Kashan area, central Iran. A total of 142 carnivores including 70 stray dogs, 40 jackals, 22 red foxes, and 10 wolves were examined for the presence of E. granulosus, as well as, 170510 slaughtered sheep, 162665 goats and 13059 cattle for hydatid cyst infection. In addition, 500 inhabitants in rural areas were examined for antibodies to hydatid cyst. Results indicated that 43.7% of carnivores were infected with E. granulosus. Infection rate in slaughtered animals was 2.7%. Overall, the seroprevalence rate in human cases was 2.4%. Eighty-five patients including 47 females and 38 males were hospitalized. The mean annual incidence rate of hydatidosis in human was three cases per 100 000 populations. In general, the situation of the hydatidosis in the livestock and human and echinococcosis in the carnivores of the Kashan is similar to the other zones in Iran.