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Toxins  2010 

Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

DOI: 10.3390/toxins2071690

Keywords: hemolysin BL, non-hemolytic enterotoxin, cytotoxin K, B. cereus

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Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.


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