All Title Author
Keywords Abstract

Molecules  2005 

Synthesis of the Key Precursor of Hirsutellide A

DOI: 10.3390/10010259

Keywords: Hirsutellide A, linear hexadepsipeptide, coupled reagent, diazotization hydrolysis, Boc protection

Full-Text   Cite this paper   Add to My Lib

Abstract:

Hexadepsipeptide 2, the precursor of Hirsutellide A (1), was synthesized in an overall yield of 45% from N-Boc-Me-Gly via three coupling reactions using dicyclohexylcarbodiimide (DCC), O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyl- uronium hexafluorophosphate (HATU) and bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl), respectively.

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

微信:OALib Journal