The collection efficiency and the emission rate of methane in a municipal solid waste landfill in Guangzhou were studied for improving the collection efficiency and reducing the emission of methane. The theoretical methane emission of 7.22×107 m3 were estimated by the US-EPA first order kinetics model, which corresponded to (2.17~2.89)×107 m3 of actual methane emission in 2010. In practice, 1.75×107 m3 of methane was collected, with the collection efficiency ranging from 60.6% to 80.6%. The operating area was the main emission source of methane, and the emission rate of methane was 0.175×107 m3·a-1 which accounted for 10.0 percent of total methane collected. The emission rates of methane in matured and fresh refuses were 4.17 mol·m-2·h-1 and 0.29 mol·m-2·h-1, respectively.