The relationship between water resource utilization and agricultural sustainable growing in the Huang Huai Hai Plain was briefly discussed in this paper. The per capita or per hectare amount of water resources in the area accounts for 29 per cent of the country's average. The grain yield per hectare is increased by 94.28kg and the total output of grains is increased by 2.05 billion kg, when the irrigation rate is increased by 1 per cent in the area. The present situation of water resource use and the environment problems of water resource utilization in the four type regions were expounded in the paper, such as water contamination and excessive exploitation of groundwater in the shallow layer in the piedmont plain region, fluorine in drinking water, funnel of groundwater and earth subsidence in the Lower Haihe Plain Region, floodwater in the Huang Huai Plain Region, running out of flood in the Huanghe River and the invasion of seawater in the coastal plain region and so on. In view of the water environment problems as said above, the adjustment and control countermeasures of water resource utilizaion were suggested, which can be used as references by the policy making departments in the districts (cities) and provinces (cities) concerned.