Mechanism of Affective and Cognitive-Control Brain Regions in Depression
抑郁症情绪加工与认知控制的脑机制

Depression is characterized by a negativity bias which is a stable factor of it. The bias reflects enhanced bottom-up responses to affective stimuli,linked to deficits in amygdala and fusiform gyrus function. Alternatively,the bias also reflects impaired top-down cognitive control,linked to deficits in dorsolateral prefrontal cortex and anterior cingulate function. A new hypothesis that the occurrence of depression is caused by interaction of increased activity in affective brain regions and deficits in cog...