全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Evaluation of Anti-Fungal Activity of Synthesized Chalcone Semicarbazone Derivatives

DOI: 10.3923/rjbsci.2011.632.634

Full-Text   Cite this paper   Add to My Lib

Abstract:

In the present study, researchers designed a Pharmacophore Model chalconesemicarbazone which is having hydrogen acceptor site, hydrogen donor site, lipophilic site, etc., using Ligandscout-2.02 software. A series of chalcone semicarbazones was synthesized and evaluated for their anti-fungal activity by Paper Disk Diffusion Method. Based on the results of an anti-fungal study, compound CS-10 was the most active compound. It was observed that methoxy substitution in aldehydic moiety and hydroxyl substitution in the acetophenic moiety significantly increased anti-microbial spectrum against fungi.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133