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Role of Widal Test in the Diagnosis of Typhoid Fever in Context to Other Test

DOI: 10.5923/j.ajb.20120201.04

Keywords: Typhoid, Widal Test

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Abstract:

Typhoid is one of the infectious diseases of human. Outbreaks of typhoid fever caused by S. typhi and S. paratyphi A are still a serious health problem worldwide. There are number of test available now days from molecular to immunological and biochemical to microbiological. In our study we have tried to establish the relevance of widal test in the diagnosis of typhoid fever. Both the tube and slide agglutination widal test were used to investigate the incidence of typhoid fever in 80 test individuals comprising 60 typhoid fever patients and 20 apparently healthy individuals comprised of adult and children. The test results were compared with those of standard blood culture tests. We tested different individuals and were categorized according to their age above 10 years (20), and between 5- 10 years (20), and children under 5 years (20). Results showed that the accuracy of the widal tube and slide agglutination tests as used in the study in terms of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 71%, 62%, 91% and 31%, respectively. It is concluded that widal test will remains relevant as a diagnosis tool for typhoid fever, which is more convenient, cheaper and faster than the other molecular and serological test.

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