objectives: to determine the risk factors associated with acute toxoplasmosis during pregnancy in armenia. methods: case-control study; 14 cases and 34 controls (mean ages 23±5.5 and 23±5.1 respectively; p = 0.93). cases were pregnant women with serological criteria for acute toxoplasmosis and controls were seronegative pregnant women for toxoplasma igg. results: the risk factors more strongly predictive of acute toxoplasmosis in pregnant women were: eating undercooked meat (or: 13.2; 95% ci: 1.3-132; p = 0.01), drinking beverages prepared with un-boiled water (or: 4.5; 95% ci: 1.1-17; p = 0.01), and contact with cats aged less than 6 months (or: undefined, p = 0.01). drinking of bottled water was a protective factor (or: 0.24; 95% ci: 0.06-0.95; p = 0.02). conclusions: 42% of toxoplasma gondii infections in pregnant women armenia were associated to contact with young cats and to consumption of undercooked meat. drinking of bottled water to prevent toxoplasma infection during pregnancy is also recommended.