surgical-site infection is a preventable adverse event. implementation of good practices for correct surgical-site preparation can contribute to lessen this safety problem. the objective of this study was to describe the presence and quality of protocols on surgical-site preparation in the murcia (spain) regional network of public hospitals. the indicator "existence of protocol for surgical-site preparation" was assessed, as well as the formal quality (expected attributes) and contents (compared to current evidence-based recommendations) of existing documents. seven of the nine hospitals have a protocol for surgical-site preparation. opportunities to improve have been identified in relation to the protocols' formal quality and contents. recommendations related to skin asepsis are incomplete and those related to hair removal contradict existing evidence. most hospitals have protocols for surgical-site preparation; however, there is great room for improvement, in relation to their expected attributes and to the inclusion of evidence-based recommendations.