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Evaluación de las alteraciones lipídicas en el síndrome de ovarios poliquísticos y su relación con la resistencia a la insulina

Keywords: polycystic ovaries syndrome, dyslipemia, insulin-resistance, lipid rates.

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Abstract:

introduction: the polycystic ovaries syndrome to exceed the reproductive axis due to its frequent association with metabolic and cardiovascular alterations. objective: based on above mentioned a cross-sectional and descriptive study was conducted to determine the frequency and the characteristic of lipid alterations en a group of women diagnosed with polycystic ovaries and its relation to alterations in insulin-sensitivity. methods: twenty three women were studied according to androgen excess society criteria, hormonal and lipid determinations were made as well as fasting glycemia and insulinemia to assess the insulin-sensitivity. results: the 95,6% of patients presenting with dyslipemia. the more frequent lipid alterations were a decrease of the high density lipoproteins (chdl) and apolipoproteins (apo) (91,3 and 87,0 %, respectively) whereas the increase of triglycerides(tg) and the total cholesterol (tc) were infrequent (13 and 4,3 %, respectively). the estimated lipid rates: tg/chdl, ct/chdl, chdl/cldl and apo b/a-i had higher mean values in women with insulin-resistance; the apo b/a-i rate had the greater difference in women with insulin-resistance and without it. conclusion: the lipid alterations frequency in study women suggest that in expression of polycystic ovaries syndrome could be involved many metabolic and hormonal factors.

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