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Disease progression after R-CHOP treatment associated with the loss of CD20 antigen expression

DOI: 10.5581/1516-8484.20110036

Keywords: lymphoma, large b-cell, diffuse, disease progression, immunotherapy.

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a case of a follicular lymphoma transformed into a cd20+ is described which progressed with the loss of cd20 expression after 8 cycles of r-chop. this phenomenon is not a rare event and has shown poor prognosis. our purposes are to describe this event and suggest biopsy in relapsed or progressive disease.


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