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Novel Insights into Disseminated Candidiasis: Pathogenesis Research and Clinical Experience Converge

DOI: 10.1371/journal.ppat.0040038

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[1]  Perlroth J, Choi B, Spellberg B (2007) Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Med Mycol 45: 321–346.
[2]  Koh AY, Kohler JR, Coggshall KT, Van Rooijen N, Pier GB (2008) Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog. 4. doi:10.1371/journal.ppat.0040035.
[3]  Clemons KV, Espiritu M, Parmar R, Stevens DA (2006) Assessment of the paradoxical effect of caspofungin in therapy of candidiasis. Antimicrob Agents Chemother 50: 1293–1297.
[4]  MacCallum DM, Odds FC (2005) Temporal events in the intravenous challenge model for experimental Candida albicans infections in female mice. Mycoses 48: 151–161.
[5]  Spellberg B, Ibrahim AS, Edwards JE Jr, Filler SG (2005) Mice with disseminated candidiasis die of progressive sepsis. J Infect Dis 192: 336–343.
[6]  Leunk RD, Moon RJ (1979) Physiological and metabolic alterations accompanying systemic candidiasis in mice. Infect Immun 26: 1035–1041.
[7]  Papadimitriou JM, Ashman RB (1986) The pathogenesis of acute systemic candidiasis in a susceptible inbred mouse strain. J Pathol 150: 257–265.
[8]  Cole GT, Halawa AA, Anaissie EJ (1996) The role of the gastrointestinal tract in hematogenous candidiasis: from the laboratory to the bedside. Clin Infect Dis 22(Suppl 2): S73–S88.
[9]  Clemons KV, Gonzalez GM, Singh G, Imai J, Espiritu M, et al. (2006) Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs. Antimicrob Agents Chemother 50: 2650–2657.
[10]  Ashman RB, Papadimitriou JM, Fulurija A, Drysdale KE, Farah CS, et al. (2003) Role of complement C5 and T lymphocytes in pathogenesis of disseminated and mucosal candidiasis in susceptible DBA/2 mice. Microb Pathog 34: 103–113.
[11]  Jensen J, Warner T, Balish E (1993) Resistance of SCID mice to Candida albicans administered intravenously or colonizing the gut: role of polymorphonuclear leukocytes and macrophages. J Infect Dis 167: 912–919.
[12]  Spellberg BJ, Johnston D, Phan QT, Edwards JE Jr, French SW, et al. (2003) Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun 71: 5756–5764.


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