The synthetic microbial community is a synthetic microbial system co-cultured with multiple species, which has the characteristics of clear composition and strong controllability. Compared with a single colony, it can achieve more complex functions and adapt to the changing environment more easily, so as to meet a wide range of needs. In this paper, the contents and concepts of microbial community and synthetic microbial community are briefly introduced, the principles that should be followed in the construction of microbial community are expounded, the methods and mathematical models used in the construction of synthetic microbial community are introduced, and the applications of synthetic microbial community in various fields are summarized. Finally, the challenges in the research of synthetic microbial communities are briefly described.
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