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Visualization of Brain Shift Corrected Functional Magnetic Resonance Imaging Data for Intraoperative Brain Mapping

DOI: 10.1016/j.wnsx.2019.100021

Keywords: Awake craniotomy, Brain mapping, Brain tumor resection, Electric stimulation, Functional mapping, Multimodal imaging, Surgical planning 2D, 2-dimensional, 3D, 3-Dimensional, CT, Computed tomography, DCS, Direct cortical stimulation, FOV, Field of view, fMRI, Functional magnetic resonance imaging, MRI, Magnetic resonance imaging, RE, Registration error, TE, Echo time, TR, Repetition time

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Abstract:

Brain tumor surgery requires careful balance between maximizing tumor excision and preserving eloquent cortex. In some cases, the surgeon may opt to perform an awake craniotomy including intraoperative mapping of brain function by direct cortical stimulation (DCS) to assist in surgical decision-making. Preoperatively, functional magnetic resonance imaging (fMRI) facilitates planning by identification of eloquent brain areas, helping to guide DCS and other aspects of the surgical plan. However, brain deformation (shift) limits the usefulness of preoperative fMRI during surgery. To address this, an integrated visualization method for fMRI and DCS results is developed that is intuitive for the surgeon

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