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- 2018
Effect of sedative agent selection on morbidity, mortality and length of stay in patients with increase in intracranial pressureDOI: 10.5847/wjem.j.1920-8642.2018.04.003 Keywords: Ketamine, Intracranial hypertension, Craniocerebral trauma, Head injury, Intubation Abstract: To identify the effects of sedative agent selection on morbidity, mortality, and length of stay in patients with suspected increase in intracranial pressure. Recent trends and developments have resulted in changes to medications that were previously utilized as pharmacological adjuncts in the sedation and intubation of patients with suspected increases in intracranial pressure. Medications that were previously considered contraindicated are now being used with increasing regularity without demonstrated safety and effectiveness. The primary objective of this study is to evaluate and compare the use of Ketamine as an induction agent for patients with increased intracranial pressure. The secondary objective was to evaluate and compare the use of Etomidate, Midazolam, and Ketamine in patients with increased intracranial pressure
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