Primary skin manifestation of non-small-cell lung cancer – a case study

Pathological processes involving internal organs can manifest themselves through a variety of skin lesions. In the case of neoplasms, these include typical paraneoplastic syndromes, which themselves do not constitute neoplastic lesions [1, 2]. More rarely, in the case of 1–12% of neoplasms, metastatic lesions from primary foci located in internal organs appear on the skin [2–6]. The involvement of the skin in the course of neoplastic diseases means that the neoplasm has gained access to the systemic circulation, which confirms its late stage and significantly worsens the prognosis. The survival time of patients with metastases to the skin is usually less than 1 year [3, 7]. An interesting phenomenon is the occurrence of a metastasis in the skin already involved in a neoplastic process, usually benign, which is referred to as a “tumour-to-tumour metastasis” [4]