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LLY-283, a Potent and Selective Inhibitor of Arginine
Methyltransferase 5, PRMT5, with Antitumor Activity
DOI: 10.1021/acsmedchemlett.8b00014
Binghui Li, Cheryl H. Arrowsmith, Dalia Barsyte-Lovejoy, Ernesto Guccione, Fengling Li, Guillermo S. Cortez, Ken Weichert, Magdalena M. Szewczyk, Mary M. Mader, Masoud Vedadi, Michael J. Grogan, Mohammad S. Eram, Peter J. Brown, Robert M. Campbell, Stephen Antonysamy, Steven Kennedy, Wayne P. Bocchinfuso, Zahid Q. Bonday
Keywords: PRMT5, methyltransferase, inhibitor, splicing, methylation
Abstract:
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