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BMS-986163, a Negative Allosteric Modulator of GluN2B
with Potential Utility in Major Depressive Disorder
DOI: 10.1021/acsmedchemlett.8b00080
Alicia Ng, Aliphedi B. Reddy, Arvind Mathur, Bettadapura N. Srikumar, Bradley C. Pearce, Charlie Albright, Charulatha Sanmathi, Dalton King, Eric Shields, G. Nagaraju, George N. Karageorge, Gopikishan Tonukunuru, Grandhi V. R.
K. M. Gupta, Huiping Zhang, Hyunsoo Park, Imadul Islam, James Kempson, Jayakumar Warrier, Jayant Aher, Jean Simmermacher, Jianliang Shi, Jianqing Li, Joanne J. Bronson, John E. Macor, Jyoti Gulia, Kumar Kuchibhotla Vijaya, Lawrence R. Marcin, Linda J. Bristow, Lorin A. Thompson, Mahesh Paschapur, Manjunath Ramarao, Manjunatha Kamble, Michael Sinz, Michelle Nophsker, Murali Subramanian, Narasimharaju Kalidindi, Pattipati S. Naidu, Rajareddy Kallem, Raju Mannoori, Reeba Vikramadithyan, Rex Denton, Richard E. Olson, Srinivas Cheruku, Srinivas Jogi, Srinivasan Thangathirupathy, Tanmaya Bastia, Thaddeus Molski, Xiaoliang Zhuo
Keywords: BMS-986163, BMS-986169, GluN2B, negative allosteric modulator, ketamine, depression, preclinical candidate
Abstract:
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