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N-Leucinyl Benzenesulfonamides
as Structurally Simplified
Leucyl-tRNA Synthetase Inhibitors
DOI: 10.1021/acsmedchemlett.7b00374
Adéla？de Saint-Leger, Aigars Jirgensons, Alex J. O’Neill, Arya Gupta, Christopher P. Randall, Daina Gustina, Daina Lola, Einars Loza, Grace Edmund, Ilze Kaula, Kristaps Jaudzems, Lluís Ribas de Pouplana, Louise Kime, Marina Madre, Michael
H. Charlton, Rihards Aleksis, Wil Goessens
Keywords: Leucyl-tRNA synthetase, inhibitors, antibacterial, sulfonamides, isothermal titration calorimetry
Abstract:
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