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-  2019 

Cancer‐associated fibroblasts show heterogeneous gene expression and induce vascular endothelial growth factor A (VEGFA) in response to environmental stimuli

DOI: 10.1002/ags3.12249

Keywords: cancer‐associated fibroblast, complex system, heterogeneity, perturbation, VEGF‐A

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Abstract:

Cancer‐associated fibroblasts (CAF) play a crucial role in angiogenesis in the complex tumor microenvironment. However, fibroblasts show extensive heterogeneity and their dynamic functions against stressors remain largely unknown

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