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-  2019 

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease

DOI: 10.1002/acn3.754

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Abstract:

Microglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+‐activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing neuroinflammation

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