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Outcomes following mepolizumab treatment discontinuation: real-world experience from an open-label trial

DOI: 10.1186/s13223-019-0348-z

Keywords: Severe eosinophilic asthma, Cessation of treatment, Asthma control, Blood eosinophils

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Abstract:

a Mean ACQ-5 scores, b geometric mean blood eosinophil counts including proportions of subjects with mean ACQ-5 score?≥?1.5/<?1.5 and blood eosinophil counts?≥?150/<?150 cells/μL. Mean ACQ-5 scores and geometric blood eosinophil counts were measured during the open label period and following treatment discontinuation. Error bars represent 95% confidence interval. Reference line for a at a mean ACQ-5 score of 1.5. Reference line for b at a geometric mean blood eosinophil count of 150 cells/μL. ACQ-5 Asthma Control Questionnaire-5, SC subcutaneou

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