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Utility of Cyclododecanone as Synthon to Synthesize Fused HeterocyclesDOI: 10.5923/j.ajoc.20120203.05 Keywords: Cyclododecanone, β-ketoesters, pyrazolones, enaminoketones, fused heterocycles. Abstract: Ethyl 2-oxocyclododecanecarboxylate (1), and 2-(hydroxyl-methylene)cyclododecanone (7) were used as key intermediates for synthesis of macrocyclic systems incorporating either fused or exocyclic nitrogen heterocycles of different ring sizes. Ring enlargement was also implemented.
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