|
Utility of Activated Nitriles in the Synthesis of Some New Heterocyclic CompoundsDOI: 10.5923/j.ajoc.20120202.06 Keywords: Cyanoacetamide, Cyanoketen N,S-acetal derivative, Enaminonitrile, 1,3-Dithiolane derivative Abstract: New 4-(2-cyanoacetamido)benzoic acid (1) was utilized as key intermediate for the synthesis of some new thiazole, pyrazole, oxazole, pyrimidine, 1,3-dithiolane, thiophene, coumarin, oxazine and pyridazine derivatives. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1H NMR and mass spectra).
|