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(D@Q<8AP@Es6[XZ[P~ttx!vJgR2~À W$tl`r1! \ȕŠ@aJn8`!s߇F'R+Pu.\ǫ`)B~ zv pڄp^BC,]`3{" .[ En؀wt >`<ܞ07`{ уKXsx wG9]q BlU[_6Y.#(IspN,qU9O_}y=3ktYv2~\"O5i/HooeErէBk7F͑}Qdz<4=%> LbC%U!Sn<*s2rQ%T1दqn*5E6M&Q xjUHPj$5N r *H S2m#CT?*KC}>2mIzQ=QTy+՝uR]-Tgu:R =kkùT+VDȆג-(STstԌJMCM&Tc5RS6*s )+%QLZ*j@&#dP}*GŰ$(JDDZ QH*UG].SeQEl<:O}K}ÒsY&ΰ4usS'q|Fc()u:,>FAc&PG>>d=&ߥvSPY7vjLsI{C^^Wj3 z}/Q|@@QZ˾繗8ZCf*Yj%4Va9˨Sԓj1AQb^=*.^ zzW/5p?Qsp/>[b\Z@NͧQsQsdm6pE3?lAP* ~<*nPU*mw@.i3i*6IeAӘiM;Iv74Q%M)xjLiRce ^6E浑2/vm5\64v=L6 0O frG ?TQqPJ)ڛEzHk[VimuP7BuV v:Jq";PK{Ԗ[jCnZq7Q7R7P׳%+[pKnBҩlF)ՄjFT*7hlg Ԑ/J) K8ɓ2y 'BQX+cXdQ"+ Q :䮠2K{p\H*ҿ瓊oJo9p|WK̝48#@| CQ?Ga 8&'~E#Cx={]v[`BRﰴѷ,7{k*=+eַX͘yI^/%7&x|Xa,ᵨy<ր`x<Vן/՗ӟBI,Oc?P?-;QQ{DL5ȼĠ!#N4ãE[sd&L-#J<|?ƸM.?\X=-[V{9U 2kx)}/9gO9p/3ظ;ne9 ,@V\wԵ6-YXZ+Խg}+ l _+|ֆ8Am2ljigiHi}p֒, Z7n: '68f@+_ŔX<&*1> RqSCbUB-(NG"lD=R{ ϰo=dĠ[=iewmo &AZir1MPB0!"脷 ^*D=p ~T!e]ITQ]nl6t@"cI,彟qWn! a smwtK]>stream hUYk@+P޻ԤCօ,IwfZN)kXf &3ŴpjfaNOhŮYQ&L>w@z{/C=ېд٦hV ݮ_"Oco:iIĥX۴J9J)Rn:UYwL iYxQcNkUBDyUnY(|v% rpGE ؝Ŷ|([m}dF+uUT+?X&mw))4E&շrl(k_)V@hke9s3K xR$]vߐGaH,=J.%`w2 @'"|#a\N0(18xfc#hmh tжOH1 $10tAL ]g`aH#kN} >stream hެmo0Qސ9I*U6"蚩M %$9݃"3<"h Ka̸$\}ʵ57(M5wJ`4YrOޓe1pK:-FVc""& 4M6$Pa-I&Pvv\TU r+)JabX$zY9N{W ZLuAڲf9-e/v 5/ f[M;H*g]-[9Xث1>`=Ɖ:,iWи|ad]BʊbF{㠨4{4љdau G]5* #~MzrDlkIHoAᙸwY;3A% dSqѲס>}] _D^Мlݛy'PN;e*:1vܮ\1`PWXB4q%)HgQݜNf,G endstream endobj 35 0 obj <>stream 2024-05-06T15:09:01+08:00 2024-05-06T15:08:59+08:00 2024-05-06T15:09:01+08:00 Acrobat PDFMaker 11 Word 版 uuid:1d6dcde3-5d77-4804-bbcf-1d7a40c3fb84 uuid:c1d768e6-bf26-4f89-a85d-83bdec967228 17 application/pdf Research Progress on Zinc Sulfide Quantum Dots in Tumor in Vivo Imaging This study elaborates on the application and unique contributions of zinc sulfide quantum dots (ZnS QDs) in tumor imaging, highlighting their significant potential in the field of nanomedicine, particularly in tumor imaging techniques. Zinc sulfide quantum dots are distinguished by their superior optical properties, chemical stability, and excellent biocompatibility. Our research focuses on the customization of ZnS QDs through integration with biocompatible compounds, and the use of covalent bonding and self-assembly techniques to incorporate fluorescent and bioactive groups. This significantly enhances imaging precision and efficiency for specific tumor markers. Furthermore, we explore zinc sulfide quantum dots with multimodal imaging capabilities, such as manganese-doped CdS quantum dots (Mn:CdS QDs). This novel discovery paves the way for precise tumor detection, localization, and treatment. Despite the promising applications of zinc sulfide quantum dots, challenges including toxicity, stability, and biocompatibility issues must be addressed in their clinical translation. Thus, this paper calls for future research to focus on developing safer and more efficient new fluorescent probes and to delve deeper into the stability and drug release characteristics of quantum dots to facilitate their use in clinical tumor diagnosis and treatment. Han He, Shuhui Huang, Jinxiao Ma, Juanli Cui, Xusheng Zhang Adobe PDF Library 11.0 Zinc Sulfide Quantum Dots, Tumor Imaging, Multimodal Imaging, Biocompatibility D:20240506070856 This study elaborates on the application and unique contributions of zinc sulfide quantum dots (ZnS QDs) in tumor imaging, highlighting their significant potential in the field of nanomedicine, particularly in tumor imaging techniques. Zinc sulfide quantum dots are distinguished by their superior optical properties, chemical stability, and excellent biocompatibility. Our research focuses on the customization of ZnS QDs through integration with biocompatible compounds, and the use of covalent bonding and self-assembly techniques to incorporate fluorescent and bioactive groups. This significantly enhances imaging precision and efficiency for specific tumor markers. Furthermore, we explore zinc sulfide quantum dots with multimodal imaging capabilities, such as manganese-doped CdS quantum dots (Mn:CdS QDs). This novel discovery paves the way for precise tumor detection, localization, and treatment. Despite the promising applications of zinc sulfide quantum dots, challenges including toxicity, stability, and biocompatibility issues must be addressed in their clinical translation. 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