Determinación de Subpoblaciones linfocitarias en lesiones de pacientes con Estomatitis Aftosa Recurrente

recurrent aphtous stomatitis (ras) is one of the most common oral mucosal diseases known. it presents as threee types: minor (most prevalent), major and herpetiform. however, not thue well established its etiology although, many evidences indicated that the patients affected with this condition have a defectous celular immune response. the objective of this study was the determination of？ the lymphocytes subpopulations t cd4+ and t cd8+ in patients with ras. we evaluated 19 patients, 15？ with minor ras and 4 with major ras.？ as a control group we included 10 patients withouth ras.？ we obtained a biopsy of each patient, that was procesed by immunohistochemistry. we observed a very high amount of lymphocytes subpopulations in the patients with ras in comparation with the control group. the results suggested the association？ of the t lymphocytes and the the celular immune response in the pathogenesis of the ras