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中国老年人握力与关节炎的关系：基于CHARLS分析
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Abstract:
目的：探讨中国老年人握力与关节炎的关系，探讨关节炎发展的潜在影响因素。方法：利用2015年中国健康与养老追踪调查(CHARLS)数据，采用多变量logistic回归分析标准化握力(握力与体重归一化)与关节炎的关系。限制三次样条(RCS)用于可视化标准化握力与关节炎风险之间的剂量–反应关系。结果：3258例关节炎患者中，随着标准化握力的升高，患关节炎的风险降低。RCS分析显示标准化握力与关节炎风险存在线性负相关关系(P总体 < 0.0006，P非线性 = 0.0818)，标准握力 > 0.49被确定为关节炎的保护阈值。结论：本研究表明，在年龄 ≥ 60岁的成年人中，标准化握力与关节炎之间存在线性负相关，握力是关节炎的保护因素。这表明，保持较高的肌肉力量可能会降低老年人患关节炎的风险。
Objective: To explore the relationship between grip strength and arthritis in Chinese elderly and to investigate the potential influencing factors of arthritis development. Methods: Using the data from the 2015 China Health and Retirement Longitudinal Survey (CHARLS), multivariate logistic regression analysis was adopted to analyze the relationship between standardized grip strength (normalization of grip strength and body weight) and arthritis. Restricted cubic splines (RCS) are used to visualize the dose-response relationship between standardized grip strength and the risk of arthritis. Result: Among the 3258 arthritis patients, the risk of arthritis decreased with the increase of standardized grip strength. RCS analysis showed that there was a linear negative correlation between standardized grip strength and the risk of arthritis (P overall < 0.0006, P nonlinearity = 0.0818), and a standard grip strength > 0.49 was determined as the protective threshold for arthritis. Conclusion: This study shows that among adults aged ≥ 60 years, there is a linear negative correlation between standardized grip strength and arthritis, and grip strength is a protective factor for arthritis. This indicates that maintaining high muscle strength may reduce the risk of arthritis in the elderly.
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