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橐吾属植物的化学成分及生物活性研究
Studies on the Chemical Constituents and Biological Activities of Ligularia Plants

DOI: 10.12677/hjas.2025.154058, PP. 472-477

Keywords: 橐吾属,化学成分,生物活性
Ligularia
, Chemical Constituents, Biological Activity

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Abstract:

橐吾属植物(Ligularia)为菊科(Compositae)千里光族(Senecioneae Cass)。橐吾属植物分布广泛,种类繁多,具有极高的药用价值。橐吾属植物化学成分多样,包括萜类、苯丙素类、黄酮类、生物碱类、甾体类等,其中倍半萜为主要成分。近几年来,诸多国内外学者对橐吾属植物开展一系列的深入研究,表明橐吾属植物具有抗菌、抗虫、抗炎、细胞毒活性等作用。本文综述了近些年来关于橐吾属植物的化学成分及生物活性的研究进展。
Ligularia plants are Compositae Senecioneae Cass. Ligularia plants are widely distributed and diverse, with high medicinal value. Ligularia plants have a variety of chemical compositions, including terpenoids, phenylpropanoids, flavonoids, alkaloids, steroids and so on, of which sesquiterpenes are the main components. In recent years, many domestic and foreign scholars have carried out a series of in-depth studies on Gewürztraminer plants, indicating that Ligularia plants have antibacterial, anthelmintic, anti-inflammatory and cytotoxic activities. This paper summarizes the progress of research on the chemical composition and biological activities of Ligularia plants in recent years.

References

[1]  刘尚武, 邓德山, 刘建全. 橐吾属的起源、演化与地理分布[J]. 植物分类学报, 1994, 32(6): 514-524.
[2]  刘守金, 戚欢阳, 齐辉, 等. 中国西北地区橐吾属植物的种类及药用资源[J]. 中国中药杂志, 2006, 31(10): 793-797.
[3]  Nagano, H., Hanai, R., Yamada, H., Matsushima, M., Miura, Y., Hoya, T., et al. (2012) Chemical and Genetic Study of Ligularia duciformis and Related Species in Sichuan and Yunnan Provinces of China. Chemistry & Biodiversity, 9, 789-805.
https://doi.org/10.1002/cbdv.201100240
[4]  Zhao, Y., Jia, Z. and Yang, L. (1994) Novel Sesquiterpenes from Ligularia veitchiana. Planta Medica, 60, 91-92.
https://doi.org/10.1055/s-2006-959418
[5]  Dong, L., Xiong, H., Qi, F., Li, H., Fan, G., Che, J., et al. (2014) A New Norsesquiterpenoid from Ligularia virgaurea. Journal of Asian Natural Products Research, 17, 415-419.
https://doi.org/10.1080/10286020.2014.971018
[6]  Saito, Y., Hattori, M., Iwamoto, Y., Takashima, Y., Mihara, K., Sasaki, Y., et al. (2011) Overlapping Chemical and Genetic Diversity in Ligularia lamarum and Ligularia subspicata. Isolation of Ten New Eremophilanes and a New Seco-Bakkane Compound. Tetrahedron, 67, 2220-2231.
https://doi.org/10.1016/j.tet.2011.01.082
[7]  Saito, Y., Hidaka, M., Fukuda, A., Okamoto, Y., Nakashima, K., Tori, M., et al. (2017) Intra-Specific Diversity of the Chemical Composition of Ligularia lamarum in the Hengduan Mountains, China: The Structures of Four New Eremophilanes and a New Seco-Eremophilane. Phytochemistry Letters, 20, 139-145.
https://doi.org/10.1016/j.phytol.2017.04.026
[8]  Wu, Q.X., Shi, Y.P. and Yang, L. (2004) Eremophilane Sesquiterpene Lactones from Ligularia virgaurea ssp. oligocephala. Planta Medica, 70, 479-482.
[9]  Saito, Y., Shiosaki, Y., Fujiwara, M., Mihara, K., Nakamizo, H., Otose, K., et al. (2018) Eremophilanes from Ligularia hookeri Collected in China and Structural Revision of 3β-Acyloxyfuranoeremophilan-15,6-olide. Chemical and Pharmaceutical Bulletin, 66, 668-673.
https://doi.org/10.1248/cpb.c18-00191
[10]  Baba, H., Yaoita, Y. and Kikuchi, M. (2007) Sesquiterpenoids from Ligularia dentata. Helvetica Chimica Acta, 90, 1302-1312.
https://doi.org/10.1002/hlca.200790131
[11]  Wang, B., Jia, Z. and Yang, X. (1997) Two Minor Benzofuranosesquiterpene Dimers from Ligularia virgaurea. Planta Medica, 63, 577-578.
https://doi.org/10.1055/s-2006-957775
[12]  Gao, X., Xie, W. and Jia, Z. (2008) Four New Terpenoids from the Roots of Ligularia narynensis. Journal of Asian Natural Products Research, 10, 185-192.
https://doi.org/10.1080/10286020701394431
[13]  Wu, Q., Liu, C., Chen, Y. and Gao, K. (2006) Terpenoids from the Roots of Ligularia muliensis. Helvetica Chimica Acta, 89, 915-922.
https://doi.org/10.1002/hlca.200690094
[14]  Lee, K., Koo, S., Jung, S., Choi, J., Jung, H. and Park, H. (2002) Structure of Three New Terpenoids, Spiciformisins a Andb, and Monocyclosqualene, Isolated from the Herbs of Ligularia fischeri var. spiciformis and Cytotoxicity. Archives of Pharmacal Research, 25, 820-823.
https://doi.org/10.1007/bf02976998
[15]  Li, P. and Jia, Z. (2008) A New Triterpene and New Sesquiterpenes from the Roots of Ligularia sagitta. Helvetica Chimica Acta, 91, 1717-1727.
https://doi.org/10.1002/hlca.200890188
[16]  Gong, Y., Meng, X. and Zhu, Y. (2018) Phytochemical and Chemotaxonomic Study on the Whole Plants of Ligularia sagitta. Biochemical Systematics and Ecology, 80, 122-127.
https://doi.org/10.1016/j.bse.2018.07.006
[17]  Gao, X. and Jia, Z.J. (2008) A New 8-O-4’-Type Neolignan from Ligularia narynensis. Chinese Chemical Letters, 19, 71-72.
https://doi.org/10.1016/j.cclet.2007.10.039
[18]  Wang, C.F., Zhao, Y., Shi, S.Y., Li, J.P., Zhang, Z.Z. and Liu, Y.Z. (2010) A New Naphthoquinone and a New Neolignan from Ligularia vellerea Rhizomes. Chemistry of Natural Compounds, 46, 184-186.
https://doi.org/10.1007/s10600-010-9563-z
[19]  Hua, L., Chen, J. and Gao, K. (2012) A New Pyrrolizidine Alkaloid and Other Constituents from the Roots of Ligularia achyrotricha (Diels) Ling. Phytochemistry Letters, 5, 541-544.
https://doi.org/10.1016/j.phytol.2012.05.009
[20]  Liu, C., Fei, D., Wu, Q. and Gao, K. (2006) Bisabolane Sesquiterpenes from the Roots of Ligularia cymbulifera. Journal of Natural Products, 69, 695-699.
https://doi.org/10.1021/np0505061
[21]  Bunyapaiboonsri, T., Yoiprommarat, S., Nopgason, R., Komwijit, S., Veeranondha, S., Puyngain, P., et al. (2014) Cadinane Sesquiterpenoids from the Basidiomycete Stereum Cf. Sanguinolentum BCC 22926. Phytochemistry, 105, 123-128.
https://doi.org/10.1016/j.phytochem.2014.06.006
[22]  Xu, Y., Nan, Z., Li, W., Huang, H. and Yuan, C. (2009) New Eremophilanolides from Ligularia hodgsonii. Helvetica Chimica Acta, 92, 209-216.
https://doi.org/10.1002/hlca.200800250
[23]  Ma, B., Gao, K., Shi, Y. and Jia, Z. (1997) Phenol Derivatives from Ligularia intermedia. Phytochemistry, 46, 915-919.
https://doi.org/10.1016/s0031-9422(97)00546-3
[24]  Lin, Y.S. (2005) Benzofuran Compounds from Ligularia caloxantha. Chinese Traditional and Herbal Drugs, 36, 335-337.
[25]  Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L., et al. (2015) Acaricidal Activity of Extracts from Ligularia virgaurea against the Sarcoptes scabiei Mite in Vitro. Experimental and Therapeutic Medicine, 10, 247-250.
https://doi.org/10.3892/etm.2015.2503
[26]  Hong, S., Joo, T. and Jhoo, J. (2015) Antioxidant and Anti-Inflammatory Activities of 3,5-Dicaffeoylquinic Acid Isolated from Ligularia fischeri Leaves. Food Science and Biotechnology, 24, 257-263.
https://doi.org/10.1007/s10068-015-0034-y
[27]  Su, J., Huang, C., Li, P., Lu, Y., Wen, Z., Kao, Y., et al. (2012) Bioactive Cadinane-Type Compounds from the Soft Coral Sinularia scabra. Archives of Pharmacal Research, 35, 779-784.
https://doi.org/10.1007/s12272-012-0503-2
[28]  Li, Q., Luo, J., Zhang, Y., Li, Z., Wang, X., Yang, M., et al. (2015) Involucratustones A-C: Unprecedented Sesquiterpene Dimers Containing Multiple Contiguous Quaternary Carbons from Stahlianthus involucratus. ChemistryA European Journal, 21, 13206-13209.
https://doi.org/10.1002/chem.201502631
[29]  Delgado, G., del Socorro Olivares, M., Chávez, M.I., Ramírez-Apan, T., Linares, E., Bye, R., et al. (2001) Antiinflammatory Constituents from Heterotheca inuloides. Journal of Natural Products, 64, 861-864.
https://doi.org/10.1021/np0005107
[30]  Pyun, C., Seo, T., Kim, D., Kim, T. and Bae, J. (2020) Protective Effects of Ligularia fischeri and Aronia melanocarpa Extracts on Alcoholic Liver Disease (in Vitro and in Vivo Study). BioMed Research International, 2020, Article ID: 9720387.
https://doi.org/10.1155/2020/9720387
[31]  Shang, Y.F., Kim, S.M., Song, D., Pan, C., Lee, W.J. and Um, B. (2010) Isolation and Identification of Antioxidant Compounds from Ligularia fischeri. Journal of Food Science, 75, C530-C535.
https://doi.org/10.1111/j.1750-3841.2010.01714.x

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