Streptococcus mutans is the most crucial cariogenic bacterium responsible for dental caries. While traditional antimicrobial agents are widely used, growing research has identified various food- and drug-derived compounds with antimicrobial, antibiofilm, and remineralization properties. These bioactive ingredients offer promising caries-preventive potential due to their effectiveness against S. mutans, biocompatibility, and minimal side effects. This review summarizes recent research progress in the study of these compounds and their potential applications in caries prevention and treatment.
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