|
|
离体牙作为植骨材料在骨增量中的应用现状及展望
|
Abstract:
本文综述了离体牙作为植骨材料在骨增量中的应用现状及未来展望。离体牙因其独特的组成和生物学特性，近年来在骨增量领域受到广泛关注。文章详细介绍了离体牙的组成与特性，阐述了其作为植骨材料的优势，包括生物相容性、骨诱导性和骨传导性。同时，探讨了离体牙在口腔种植、颌面外科和骨科等领域的应用现状。此外，还分析了离体牙植骨材料面临的主要挑战，并展望了未来的研究方向。研究表明，离体牙作为一种潜在的植骨材料，在骨增量领域具有广阔的应用前景。
This article reviews the current application status and future prospects of extracted teeth as bone graft materials in bone augmentation. Due to their unique composition and biological properties, extracted teeth have garnered significant attention in the field of bone augmentation in recent years. The article elaborates on the composition and characteristics of extracted teeth, highlighting their advantages as bone graft materials, including biocompatibility, osteoinductivity, and osteoconductivity. It also explores the current applications of extracted teeth in dental implants, maxillofacial surgery, and orthopedics. Furthermore, the main challenges faced by extracted teeth as bone graft materials are analyzed, and future research directions are proposed. Studies indicate that extracted teeth, as a potential bone graft material, hold broad application prospects in the field of bone augmentation.
| [1] | Sculean, A., Nikolidakis, D., Nikou, G., Ivanovic, A., Chapple, I.L.C. and Stavropoulos, A. (2015) Biomaterials for Promoting Periodontal Regeneration in Human Intrabony Defects: A Systematic Review. Periodontology 2000, 68, 182-216. https://doi.org/10.1111/prd.12086 |
| [2] | Misch, C.M. (2022) Autogenous Bone Is Still the Gold Standard of Graft Materials in 2022. Journal of Oral Implantology, 48, 169-170. https://doi.org/10.1563/aaid-joi-d-22-editorial.4803 |
| [3] | Kima, S., Yeoa, H. and Kimb, Y. (1999) Grafting of Large Defects of the Jaws with a Particulate Dentin-Plaster of Paris Combination. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 88, 22-25. https://doi.org/10.1016/s1079-2104(99)70188-5 |
| [4] | Mehboob, H., Mehboob, A., Abbassi, F., Ahmad, F., Khan, A.S. and Miran, S. (2021) Bioinspired Porous Dental Implants Using the Concept of 3D Printing to Investigate the Effect of Implant Type and Porosity on Patient’s Bone Condition. Mechanics of Advanced Materials and Structures, 29, 6011-6025. https://doi.org/10.1080/15376494.2021.1971347 |
| [5] | 申丁. 煮沸处理牙本质颗粒作为骨移植材料的实验研究[D]: [硕士学位论文]. 大连: 大连医科大学, 2016. |
| [6] | Titsinides, S., Agrogiannis, G. and Karatzas, T. (2019) Bone Grafting Materials in Dentoalveolar Reconstruction: A Comprehensive Review. Japanese Dental Science Review, 55, 26-32. https://doi.org/10.1016/j.jdsr.2018.09.003 |
| [7] | Hoexter, D.L. (2002) Bone Regeneration Graft Materials. Journal of Oral Implantology, 28, 290-294. https://doi.org/10.1563/1548-1336(2002)028<0290:brgm>2.3.co;2 |
| [8] | Bandyopadhyay, A., Mitra, I. and Bose, S. (2020) 3D Printing for Bone Regeneration. Current Osteoporosis Reports, 18, 505-514. https://doi.org/10.1007/s11914-020-00606-2 |
| [9] | Ren, J., Li, Z., Liu, W., Fan, Y., Qi, L., Li, S., et al. (2024) Demineralized Bone Matrix for Repair and Regeneration of Maxillofacial Defects: A Narrative Review. Journal of Dentistry, 143, 104899. https://doi.org/10.1016/j.jdent.2024.104899 |
| [10] | Umebayashi, M., Ohba, S., Kurogi, T., Noda, S. and Asahina, I. (2020) Full Regeneration of Maxillary Alveolar Bone Using Autogenous Partially Demineralized Dentin Matrix and Particulate Cancellous Bone and Marrow for Implant-Supported Full Arch Rehabilitation. Journal of Oral Implantology, 46, 122-127. https://doi.org/10.1563/aaid-joi-d-19-00315 |
| [11] | Sultan, N. and Jayash, S.N. (2024) In vivo Evaluation of Regenerative Osteogenic Potential Using a Human Demineralized Dentin Matrix for Dental Application. Dentistry Journal, 12, Article 76. https://doi.org/10.3390/dj12030076 |
| [12] | Khurshid, Z., Adanir, N., Ratnayake, J., Dias, G. and Cooper, P.R. (2024) Demineralized Dentin Matrix for Bone Regeneration in Dentistry: A Critical Update. The Saudi Dental Journal, 36, 443-450. https://doi.org/10.1016/j.sdentj.2023.11.028 |
| [13] | 马程辉. 不同处理方法对未脱钙人牙本质颗粒的抗原性和成骨效果影响的实验研究[D]: [硕士学位论文]. 大连: 大连医科大学, 2017. |
| [14] | Goldberg, M. (2011) Dentin Structure Composition and Mineralization. Frontiers in Bioscience, 3, 711-735. https://doi.org/10.2741/e281 |
| [15] | Roberts-Clark, D.J. and Smith, A.J. (2000) Angiogenic Growth Factors in Human Dentine Matrix. Archives of Oral Biology, 45, 1013-1016. https://doi.org/10.1016/s0003-9969(00)00075-3 |
| [16] | Elkady, E., Nour El-den, R., Atiba, A. and Yasser, S. (2023) Comparing the Effect of Demineralized versus Hybrid Dentin Matrices on Inducing Bone Regeneration in New Zealand White Rabbits’ Mandibular Defect. Journal of Stomatology, Oral and Maxillofacial Surgery, 124, Article 101346. https://doi.org/10.1016/j.jormas.2022.11.022 |
| [17] | Kim, Y., Lee, J., Um, I. and Cho, W. (2016) Guided Bone Regeneration Using Demineralized Dentin Matrix: Long-Term Follow-up. Journal of Oral and Maxillofacial Surgery, 74, 515.E1-515.E9. https://doi.org/10.1016/j.joms.2015.10.030 |
| [18] | Bormann, K., Suarez-Cunqueiro, M.M., Sinikovic, B., Kampmann, A., von See, C., Tavassol, F., et al. (2012) Dentin as a Suitable Bone Substitute Comparable to ß-TCP—An Experimental Study in Mice. Microvascular Research, 84, 116-122. https://doi.org/10.1016/j.mvr.2012.06.004 |
| [19] | Wang, F., Xie, C., Ren, N., Bai, S. and Zhao, Y. (2019) Human Freeze-Dried Dentin Matrix as a Biologically Active Scaffold for Tooth Tissue Engineering. Journal of Endodontics, 45, 1321-1331. https://doi.org/10.1016/j.joen.2019.08.006 |
| [20] | Alqutaibi, A.Y., Alnazzawi, A.A. and Farghal, A. (2023) Autogenous Dentin Grafts Have Comparable Short-Term Outcomes to Other Graft Materials Regarding Implant Stability, Preimplant Marginal Bone Loss, and Complication Rate. Journal of Evidence-Based Dental Practice, 23, Article 101844. https://doi.org/10.1016/j.jebdp.2023.101844 |
| [21] | Feng, Y., Zhao, R., Li, J., Yuan, Z., Xu, X. and Gong, J. (2023) Efficacy of Autogenous Particulated Dentin Graft for Alveolar Ridge Preservation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Medicine, 102, e36391. https://doi.org/10.1097/md.0000000000036391 |
| [22] | Kim, Y., Kim, S., Byeon, J., Lee, H., Um, I., Lim, S., et al. (2010) Development of a Novel Bone Grafting Material Using Autogenous Teeth. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 109, 496-503. https://doi.org/10.1016/j.tripleo.2009.10.017 |
| [23] | Mateu-Sanz, M., Fuenteslópez, C.V., Uribe-Gomez, J., Haugen, H.J., Pandit, A., Ginebra, M., et al. (2024) Redefining Biomaterial Biocompatibility: Challenges for Artificial Intelligence and Text Mining. Trends in Biotechnology, 42, 402-417. https://doi.org/10.1016/j.tibtech.2023.09.015 |
| [24] | Park, S., Kim, D. and Pang, E. (2017) Bone Formation of Demineralized Human Dentin Block Graft with Different Demineralization Time: In Vitro and in Vivo Study. Journal of Cranio-Maxillofacial Surgery, 45, 903-912. https://doi.org/10.1016/j.jcms.2017.03.007 |
| [25] | Mahardawi, B., Jiaranuchart, S., Dhanesuan, K., Arunjaroensuk, S., Mattheos, N. and Pimkhaokham, A. (2023) Correction to: The Clinical Efficacy of the Allogenic Demineralized Dentin Matrix Graft for Implant Placement: A Systematic Review. Oral and Maxillofacial Surgery, 28, 1005-1005. https://doi.org/10.1007/s10006-023-01171-5 |
| [26] | Wang, T. and Guo, Y. (2024) The Host Response to Autogenous, Allogeneic, and Xenogeneic Treated Dentin Matrix/Demineralized Dentin Matrix-Oriented Tissue Regeneration. Tissue Engineering Part B: Reviews, 30, 74-81. https://doi.org/10.1089/ten.teb.2023.0065 |
| [27] | Minetti, E., Palermo, A., Malcangi, G., Inchingolo, A.D., Mancini, A., Dipalma, G., et al. (2023) Dentin, Dentin Graft, and Bone Graft: Microscopic and Spectroscopic Analysis. Journal of Functional Biomaterials, 14, Article 272. https://doi.org/10.3390/jfb14050272 |
| [28] | Copelli, F.A., de Lima, A.A.S., de Oliveira Santos, C.C., Carneiro, E. and Cavenago, B.C. (2021) Biological Response to Lyophilized Demineralized Dentin Matrix Implanted in the Subcutaneous Tissues of Rats. The Saudi Dental Journal, 33, 441-447. https://doi.org/10.1016/j.sdentj.2020.12.005 |
| [29] | Um, I., Lee, J., Kim, J., Kim, Y., Bakhshalian, N., Jeong, Y.K., et al. (2021) Allogeneic Dentin Graft: A Review on Its Osteoinductivity and Antigenicity. Materials, 14, Article 1713. https://doi.org/10.3390/ma14071713 |
| [30] | Ku, J., Jeong, Y.K. and Um, I. (2021) Review of Allogeneic Dentin Graft for Maxillofacial Bone Defects. Tissue Engineering Part C: Methods, 27, 472-480. https://doi.org/10.1089/ten.tec.2021.0152 |
| [31] | Jiao, L., Xie, L., Yang, B., Yu, M., Jiang, Z., Feng, L., et al. (2014) Cryopreserved Dentin Matrix as a Scaffold Material for Dentin-Pulp Tissue Regeneration. Biomaterials, 35, 4929-4939. https://doi.org/10.1016/j.biomaterials.2014.03.016 |
| [32] | Wingenfeld, C., Egli, R.J., Hempfing, A., Ganz, R. and Leunig, M. (2002) Cryopreservation of Osteochondral Allografts: Dimethyl Sulfoxide Promotes Angiogenesis and Immune Tolerance in Mice. The Journal of Bone & Joint Surgery, 84, 1420-1429. https://doi.org/10.2106/00004623-200208000-00019 |
| [33] | Mirkhalaf, M., Men, Y., Wang, R., No, Y. and Zreiqat, H. (2022) Personalized 3D Printed Bone Scaffolds: A Review. Acta Biomaterialia, 156, 110-124. https://doi.org/10.1016/j.actbio.2022.04.014 |
| [34] | Lee, J., Seo, H., Cho, Y., Sung, I. and Son, J. (2024) Addition of Recombinant Human Bone Morphogenic Protein-2 to the Graft Materials Improves the Clinical Outcomes of Implants Placed in Grafted Maxillary Sinus. Journal of Dental Sciences, 19, 865-870. https://doi.org/10.1016/j.jds.2023.08.020 |
| [35] | Ku, J., Choi, J., Song, S., Yun, P., Um, I. and Leem, D.H. (2024) Demineralized Dentin Matrix Incorporated with Rhbmp-2 Composite Graft for Treating Medication-Related Osteonecrosis of the Jaw. Journal of Clinical Medicine, 13, Article 4830. https://doi.org/10.3390/jcm13164830 |
